Boronic Acid → HCID 86672855, compound

HRID 1397035Notes

Reaction equation

HRID 1397035 reaction equation
B(O)O.Br[C:5]1[CH:12]=[C:11]([F:13])[CH:10]=[CH:9][C:6]=1[CH:7]=[O:8].[O:14]1[CH:18]=[CH:17][CH:16]=[C:15]1B(O)O>>[F:13][C:11]1[CH:10]=[CH:9][C:6]([CH:7]=[O:8])=[C:5]([C:15]2[O:14][CH:18]=[CH:17][CH:16]=2)[CH:12]=1

Participants

4

Reactant 3

HCID 61668Boronic AcidHCID 2734357Furan-2-boronic acidHCID 27733192-Bromo-4-fluorobenzaldehyde

Product 1

HCID 86672855HCID 86672855, compound

Procedure

4-fluoro-2-(furan-2-yl)benzaldehyde was prepared using the general boronic acid coupling procedure with 2-bromo-4-fluorobenzaldehyde and furan-2-ylboronic acid (20 mg, 94 mg theoretical, 21.3%). LC-MS m/z 191 (M+1).

Sources & evidence

ORD record
ord-72c017389721407288101a3442a07aad
Source dataset
uspto-grants-2014_12
Patent number
US08901145B2

Reaction notes

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