HuagongsheHuagongshe Chemistry Print Report · For research reference only
piperidine N,N-dimethylformamide → Benzyl Nepsilon-(t-butoxycarbonyl)-L-lysine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | piperidine N,N-dimethylformamide | HCID 23501187 | — |
| Reactant | Benzyl Nalpha-(9-fluorenylmethoxycarbonyl)-Nepsilon-(t-butoxycarbonyl)-L-lysine | HCID 86666529 | — |
| Product | Benzyl Nepsilon-(t-butoxycarbonyl)-L-lysine | HCID 86666528 | — |
Reaction Steps
Fmoc protected amino acid 48 (1.0 g, 1.79 mmol) was treated with a solution of piperidine/DMF (9 mL, 5% v/v) and stirred for 20 min then concentrated to dryness and used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901072B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-187bc8e3b64342b29a9ed6fc5110722e |
| Source note | uspto-grants-2014_12 |