HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 66632736, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Reactant | HCID 66632972 | HCID 66632972 | — |
| Reactant | HCID 86663641 | HCID 86663641 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 66632736 | HCID 66632736 | — |
Reaction Steps
To a solution of 3-[5-Fluoro-2-(2-methoxycarbonyl-ethyl)-benzyl]-7-oxa-bicyclo[2.2.1]heptane-2-carboxylic acid (5 g, 14.86 mmol) and nonylserinamide (3.77 g, 16.35 mmol) in dimethylformamide (150 ml) under nitrogen atmosphere, N-methylmorpholine (3.6 mL, 32.7 mmol) was added followed by HBTU (6.2 g, 16.35 mmol). The resulting mixture was stirred at room temperature for 16 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901159B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-2247c8733fc84e679e21a40a0814b77c |
| Source note | uspto-grants-2014_12 |