3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 69949904, compound

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Reaction Steps

This compound was synthesized from (1-(4-phenylthiazol-2-yl)cyclopentyl)methanamine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (65 mg, yield 34%). 1H NMR (400 MHz, DMSO-d6) 8.78 (m, 1H), 8.44 (s, 1H), 8.19 (d, J=7.6 Hz, 1H), 8.06 (d, J=7.9 Hz, 1H), 7.98 (s, 1H), 7.93 (d, J=7.3 Hz, 2H), 7.71 (t, J=7.9 Hz, 1H), 7.39 (m, 2H), 7.30 (m, 1H), 3.69 (d, J=6.2 Hz, 2H), 2.19 (m, 2H), 2.07 (m, 2H), 1.76 (m, 2H), 1.64 (m, 2H). MS (ESI) m/z: Calculated for C25H21F3N4O2S: 498.13. found: 499.2 (M+H)+.

Provenance & Evidence