3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 67346828, compound

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Reaction Steps

This compound was synthesized from 2-methyl-2-(4-phenylthiazol-2-yl)propan-1-amine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (75 mg, yield 38%). 1H NMR (400 MHz, MeOD) δ 8.52 (t, J=1.8 Hz, 1H), 8.27 (d, J=7.8 Hz, 1H), 8.03 (d, J=8.0 Hz, 1H), 7.92-7.90 (m, 2H), 7.69 (s, 1H), 7.67-7.63 (t, J=7.8 Hz, 1H), 7.36-7.29 (m, 2H), 7.28-7.26 (m, 1H), 3.79 (d, J=6.3 Hz, 2H), 1.58 (s, 6H). MS (ESI) m/z: Calculated for C23H19F3N4O2S: 472.12. found: 473.0 (M+H)+.

Provenance & Evidence