HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyanoethanethioamide → 2-(4-Cyclohexylthiazol-2-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyanoethanethioamide | HCID 1416277 | — |
| Reactant | 2-Bromo-1-cyclohexylethanone | HCID 11160027 | — |
| Product | 2-(4-Cyclohexylthiazol-2-yl)acetonitrile | HCID 43235129 | 80% |
Reaction Steps
This compound was synthesized from 2-bromo-1-cyclohexylethanone and 2-cyanothioacetamide as described in example 1 step 1 (0.4 g, yield 80%). 1H NMR (300 MHz, CDCl3) δ 6.88 (s, 1H), 4.11 (s, 2H), 2.74 (m, 1H), 2.06-2.04 (m, 2H), 1.84-1.72 (m, 4H), 1.44-1.31 (m, 4H). MS (ESI) m/z: Calculated for C11H14N2S: 206.09. found: 207.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-f4ee06f70ffb44e4ba42a14c9495dd3e |
| Source note | uspto-grants-2014_12 |