2-Cyanoethanethioamide → HCID 1095923, compound

HRID 1397241Notes

Reaction equation

HRID 1397241 reaction equation
Br[CH2:2][C:3]([C:5]1[S:6][CH:7]=[CH:8][CH:9]=1)=O.[C:10]([CH2:12][C:13]([NH2:15])=[S:14])#[N:11]>>[S:6]1[CH:7]=[CH:8][CH:9]=[C:5]1[C:3]1[N:15]=[C:13]([CH2:12][C:10]#[N:11])[S:14][CH:2]=1

Participants

3

Reactant 2

HCID 14162772-CyanoethanethioamideHCID 27763722-Bromo-1-(thiophen-2-yl)ethan-1-one

Product 1

HCID 1095923HCID 1095923, compoundYield 49%

Procedure

This compound was synthesized from 2-bromo-1-(thiophen-2-yl)ethanone and 2-cyanothioacetamide as described in example 1 step 1 (0.25 g, yield 49%): 1H NMR (400 MHz, CDCl3) δ 7.47 (d, J=3.4 Hz, 1H), 7.36 (s, 1H), 7.33 (d, J=5.1 Hz, 1H), 7.09 (t, J=4.2 Hz, 1H), 4.17 (s, 2H). MS (ESI) m/z: Calculated for C9H6N2S2: 206.00. found: 207.0 (M+H)+.

Sources & evidence

ORD record
ord-686503efb45b48b5aea9e11aad8938b0
Source dataset
uspto-grants-2014_12
Patent number
US08901156B2

Reaction notes

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