3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 67323915, compound

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Reaction Steps

This compound was synthesized from 2-(4-(4-chlorophenyl)thiazol-2-yl)-2-methylpropan-1-amine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (80 mg, yield 35%): 1H NMR (400 MHz, CDCl3) δ 8.54 (m, 1H), 8.27 (d, J=7.8 Hz, 1H), 8.10-8.04 (m, 2H), 7.82-7.80 (d, J=8.5 Hz, 2H), −7.62-7.58 (t, J=7.8 Hz, 1H), 7.42 (s, 1H), 7.33 (d, J=8.5 Hz, 2H), 3.82 (d, J=5.8 Hz, 2H), 1.58 (s, 6H). MS (ESI) m/z: Calculated for C23H18ClF3N4O2S: 506.08. found: 507.0 (M+H)+.

Provenance & Evidence