HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67324294, compound → HCID 69949932, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67324294 | HCID 67324294 | — |
| Reactant | HCID 67326264 | HCID 67326264 | — |
| Product | HCID 69949932 | HCID 69949932 | 32% |
Reaction Steps
This compound was synthesized from 2-(4-(4-fluorophenyl)thiazol-2-yl)-2-methylpropan-1-amine and 3-fluoro-5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (23 mg, yield 32%): 1H NMR (400 MHz, CDCl3) δ 8.32 (br s, 1H), 8.23 (br t, J=5 Hz, 1H), 7.94 (br d, J=8 Hz, 1H), 7.86-7.75 (m, 3H), 7.06-7.00 (m, 2H), 3.78 (d, J=4 Hz, 2H), 1.55, (s, 6H). MS (ESI) m/z: Calculated for C23H17F6N4O2S: 508.10. found: 509.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-586ea2a6093c432abb568442a45f9cd1 |
| Source note | uspto-grants-2014_12 |