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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397269Generated: November 1, 2026

3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 71487698, compound

https://huagongshe.com/reaction/1397269

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acidHCID 25180854—
ReactantHCID 67324389HCID 67324389—
ProductHCID 71487698HCID 7148769824%

Reaction Steps

This compound was synthesized from 2-methyl-2-(4-(4-(trifluoromethyl)phenyl)thiazol-2-yl)propan-1-amine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (10 mgs, 24% yield). 1H NMR (300 MHz, CDCl3) δ 8.51 (s, 1H), 8.25 (d, J=7.4 Hz, 1H), 8.09-7.96 (m, 4H), 7.64-7.53 (m, 3H), 3.82 (bs, 2H), 1.56 (s, 6H). MS (ESI) m/z: Calculated for C24H18F6N4O2S: 540.11. found: 541.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901156B2
Source datasetuspto-grants-2014_12
ORD IDord-86d609ffccae4e468522530ecb4d3385
Source noteuspto-grants-2014_12