HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67324009, compound → HCID 67325032, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67324009 | HCID 67324009 | — |
| Reactant | HCID 67325263 | HCID 67325263 | — |
| Product | HCID 67325032 | HCID 67325032 | 56% |
Reaction Steps
This compound was synthesized from 6-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)picolinic acid and 2-(4-(4-chlorophenyl)thiazol-2-yl)-2-methylpropan-1-amine as described in example 8 step 6 (55 mg, yield 56%). 1H NMR (400 MHz, CDCl3) δ 8.87-8.85 (m, 1H), 8.43-8.41 (dd, J=7.8 Hz, 1 Hz, 1H), 8.27-8.24 (dd, J=7.8 Hz, 1.3 Hz, 1H), 8.10-8.06 (m, 1H), 7.89-7.87 (d, J=8.5 Hz, 2H), 7.41 (s, 1H), 7.32-7.29 (d, J=8.8 Hz, 2H), 3.91-3.89 (d, J=6.5 Hz, 2H), 1.56 (s, 6H). MS (ESI) m/z: Calculated for C22H17ClF3N6O2S: 507.07. found: 508.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-4e08314abda3428a81112b4bde3c23d5 |
| Source note | uspto-grants-2014_12 |