3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 69950076, compound

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Reaction Steps

This compound was synthesized from (1-(4-phenylthiazol-2-yl)cyclopropyl)methanamine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (47 mg, yield 49%). 1H NMR (400 MHz, CDCl3) δ 8.59 (s, 1H), 8.25-8.23 (m, 2H), 8.09-8.07 (m, 1H), 7.90-7.88 (m, 2H), 7.63-7.59 (t, J=7.9 Hz, 1H), 7.41-7.38 (m, 2H), 7.35-7.33 (m, 1H), 7.32 (s, 1H), 3.93 (d, J=5.5 Hz, 2H), 1.42-1.39 (m, 2H), 1.23-1.20 (m, 2H). MS (ESI) m/z: Calculated for C23H17F3N4O2S: 470.10. found: 471.0 (M+H)+.

Provenance & Evidence