(4-phenyl-1,3-thiazol-2-yl)methanamine → HCID 67347482, compound

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Reaction Steps

This compound was synthesized from (4-phenylthiazol-2-yl)methanamine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (60 mg, yield 38%) as a white solid. 1H NMR (400 MHz, CDCl3) δ 8.59 (m, 1H), 8.31-8.29 (dd, J=7.8 Hz, 1.0 Hz, 1H), 8.12-8.10 (m, 1H), 7.91-7.89 (m, 2H), 7.67 (t, J=7.8 Hz, 1H), 7.47 (s, 1H), 7.44 (t, J=7.5 Hz, 2H), 7.38-7.34 (m, 1H), 7.23 (t, J=4.8 Hz, 1H), 5.04 (d, J=5.5 Hz, 2H). MS (ESI) m/z: Calculated for C20H13F3N4O2S: 430.07. found: 431.0 (M+H)+.

Provenance & Evidence