2-[2-(4-Fluorophenyl)-1,3-thiazol-4-yl]ethan-1-amine → HCID 67346226, compound

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Reaction Steps

This compound was synthesized from 2-(2-(4-fluorophenyl)thiazol-4-yl)ethanamine and 5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid as described in example 8 step 6 (30 mg, yield 17%). 1H NMR (400 MHz, DMSO-d6) δ 9.45 (br s, 1H), 9.26 (br s, 1H), 8.82 (t, J=2.0 Hz, 1H), 7.96-7.92 (m, 3H), 7.14-7.08 (m, 3H), 3.94-3.89 (m, 2H), 3.19-3.16 (m, 2H). MS (ESI) m/z: Calculated for C20H13F4N5O2S: 463.07. found: 464.0 (M+H)+.

Provenance & Evidence