2-[2-(4-Fluorophenyl)-1,3-thiazol-4-yl]ethan-1-amine → HCID 69950214, compound

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Reaction Steps

This compound was synthesized from 2-(2-(4-fluorophenyl)thiazol-4-yl)ethanamine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (60 mg, yield 45%). 1H NMR (400 MHz, CDCl3) δ 8.53 (t, J=1.4 Hz, 1H), 8.27-8.24 (dt, J=7.9 Hz, 1.3 Hz, 1H), 8.09-8.06 (dt, J=7.6 Hz, 1.6 Hz, 1H), 7.94-7.90 (m, 2H), 7.70 (m, 1H), 7.63-7.59 (t, J=7.8 Hz, 1H), 7.09-7.05 (m, 3H), 3.91-3.86 (m, 2H), 3.16-3.13 (t, J=6.0 Hz, 2H). MS (ESI) m/z: Calculated for C21H14F4N4O2S: 462.08. found: 463.0 (M+H)+.

Provenance & Evidence