3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 67325025, compound

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Reaction Steps

This compound was synthesized from 2-(3-(4-chlorophenyl)-1H-1,2,4-triazol-5-yl)ethanamine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (15 mg, yield 13%). 1H NMR (400 MHz, CDCl3) δ 8.53 (s, 1H), 8.28-8.26 (d, J=7.8 Hz, 1H), 8.09-8.06 (m, 1H), 8.02-8.00 (d, J=8.5 Hz, 2H), 7.65-7.61 (t, J=7.8 Hz, 1H), 7.56-7.53 (m, 1H), 7.42-7.40 (d, J=8.5 Hz, 2H), 4.03-3.96 (q, J=6.0 Hz, 2H), 3.25-3.22 (d, J=6.0 Hz, 2H). MS (ESI) m/z: Calculated for C20H14ClF3N6O2: 462.08. found: 463.0 (M+H)+.

Provenance & Evidence