HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67324009, compound → HCID 69950206, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67324009 | HCID 67324009 | — |
| Reactant | HCID 67324110 | HCID 67324110 | — |
| Product | HCID 69950206 | HCID 69950206 | 59% |
Reaction Steps
This compound was synthesized from 2-(4-(4-chlorophenyl)thiazol-2-yl)-2-methylpropan-1-amine and 6-methyl-5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid as described in example 8 step 6 (28 mg, yield 59%). 1H NMR (400 MHz, CDCl3) δ 9.11 (br s, 1H), 8.80 (br s, 1H), 8.07 (br s, 1H), 7.79-7.77 (d, J=8.8 Hz, 2H), 7.43 (s, 1H), 7.35-7.33 (d, J=8.8 Hz, 2H), 3.86-3.84 (d, J=5.5 Hz, 2H), 3.02 (s, 3H), 1.57 (s, 6H). MS (ESI) m/z: Calculated for C23H19ClF3N5O2S: 521.09. found: 522.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-89599a56980b44e996fa48b532c1871a |
| Source note | uspto-grants-2014_12 |