3-(4-Phenylthiazol-2-yl)propan-1-amine → N-(3-(4-Phenylthiazol-2-yl)propyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide

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Reaction Steps

This compound was synthesized from 3-(4-phenylthiazol-2-yl)propan-1-amine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (100 mg, yield 70%). 1H NMR (400 MHz, CDCl3) δ 8.40 (m, 1H), 8.17-8.14 (m, 1H), 7.96-7.94 (m, 1H), 7.80-7.78 (m, 2H), 7.45-7.41 (m, 1H), 7.34-7.29 (m, 4H), 3.70-3.66 (q, J=6.3 Hz, 2H), 3.27-3.23 (t, J=6.7 Hz, 2H), 2.29-2.23 (m, 2H). MS (ESI) m/z: Calculated for C22H17F3N4O2S: 458.10. found: 459.2 (M+H)+.

Provenance & Evidence