HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67324009, compound → HCID 67325730, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67324009 | HCID 67324009 | — |
| Reactant | 5-Cyano-2-methyl-3-pyridinecarboxylic acid | HCID 67325584 | — |
| Product | HCID 67325730 | HCID 67325730 | 46% |
Reaction Steps
This compound was synthesized from 2-(4-(4-chlorophenyl)thiazol-2-yl)-2-methylpropan-1-amine and 5-cyano-2-methylnicotinic acid as described in example 8 step 6 (200 mg, yield 46%). 1H NMR (300 MHz, CDCl3) δ 8.81 (m, 1H), 8.00-7.99 (m, 1H), 7.70-7.67 (m, 2H), 7.50-7.46 (m, 1H), 7.41-7.37 (m, 3H), 3.81-3.79 (d, J=5.7 Hz, 2H), 2.81 (s, 3H), 1.57 (s, 6H). MS (ESI) m/z: Calculated for C21H19ClN4OS: 410.10. found: 411.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-c676993362e744df98ea9af9bae03335 |
| Source note | uspto-grants-2014_12 |