HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 4-Chlorobenzamide | HCID 12084 | — |
| Product | 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole | HCID 7131527 | 46% |
Reaction Steps
This compound was synthesized from 4-chlorobenzamide and 1,3-dichloroacetone as described in example 74 step 1 (3.4 g, yield 46%). 1H NMR (300 MHz, CDCl3) δ 8.01-7.98 (d, J=8.8 Hz, 2H), 7.72 (s, 1H), 7.47-7.44 (d, J=8.8 Hz, 2H), 4.59 (d, J=0.9 Hz, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-d9b1504ad1504f958a9f5bc2eb69f58b |
| Source note | uspto-grants-2014_12 |