3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 67346279, compound

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Reaction Steps

This compound was synthesized from 2-(2-(4-fluorophenyl)oxazol-5-yl)ethanamine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (28 mg, yield 20%). 1H NMR (400 MHz, MeOD) δ 8.56-8.55 (m, 1H), 8.30-8.28 (dq, J=7.8 Hz, 0.9 Hz, 1H), 8.06-8.04 (m, 1H), 8.00-7.96 (dd, J=9.0 Hz, 5.3 Hz, 2H), 7.71-7.69 (t, J=7.8 Hz, 1H), 7.21-7.17 (t, J=8.8 Hz, 2H), 7.03 (s, 1H), 3.78-3.75 (t, J=6.7 Hz, 2H), 3.15-3.12 (m, 2H). MS (ESI) m/z: Calculated for C21H14F4N4O3: 446.10. found: 447.0 (M+H)+.

Provenance & Evidence