HuagongsheHuagongshe Chemistry Print Report · For research reference only
1000931-48-5 → HCID 67379524, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1000931-48-5 | HCID 18071419 | — |
| Reactant | 5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid | HCID 67324216 | — |
| Product | HCID 67379524 | HCID 67379524 | 19% |
Reaction Steps
This compound was synthesized from 2-(2-(4-methoxyphenyl)oxazol-4-yl)ethanamine and 5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid as described in example 8 step 6 (35 mg, yield 19%) as a white solid. 1H NMR (400 MHz, CDCl3) δ 9.47 (m, 1H), 9.34 (m, 1H), 8.90-8.89 (t, J=2.0 Hz, 1H), 8.08-8.06 (m, 1H), 8.03-8.00 (d, J=8.8 Hz, 2H), 7.55 (s, 1H), 6.99-6.97 (d, J=8.8 Hz, 2H), 3.88 (s, 3H), 3.87-3.84 (m, 2H), 2.96-2.93 (t, J=5.9 Hz, 2H). MS (ESI) m/z: Calculated for C21H16F3N5O4: 459.12. found: 460.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-65e5cb431d2d440c96893a2bde091b99 |
| Source note | uspto-grants-2014_12 |