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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397416Generated: October 30, 2026

1000931-48-5 → HCID 67379524, compound

https://huagongshe.com/reaction/1397416

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1000931-48-5HCID 18071419—
Reactant5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acidHCID 67324216—
ProductHCID 67379524HCID 6737952419%

Reaction Steps

This compound was synthesized from 2-(2-(4-methoxyphenyl)oxazol-4-yl)ethanamine and 5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid as described in example 8 step 6 (35 mg, yield 19%) as a white solid. 1H NMR (400 MHz, CDCl3) δ 9.47 (m, 1H), 9.34 (m, 1H), 8.90-8.89 (t, J=2.0 Hz, 1H), 8.08-8.06 (m, 1H), 8.03-8.00 (d, J=8.8 Hz, 2H), 7.55 (s, 1H), 6.99-6.97 (d, J=8.8 Hz, 2H), 3.88 (s, 3H), 3.87-3.84 (m, 2H), 2.96-2.93 (t, J=5.9 Hz, 2H). MS (ESI) m/z: Calculated for C21H16F3N5O4: 459.12. found: 460.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901156B2
Source datasetuspto-grants-2014_12
ORD IDord-65e5cb431d2d440c96893a2bde091b99
Source noteuspto-grants-2014_12