HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 67324431, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid | HCID 25180854 | — |
| Reactant | 2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine | HCID 67323086 | — |
| Product | HCID 67324431 | HCID 67324431 | 12% |
Reaction Steps
This compound was synthesized from 2-(2-(4-fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (18 mg, yield 12%). 1H NMR (400 MHz, MeOD) δ 8.55 (s, 1H), 8.29 (d, J=7.8 Hz, 1H), 8.09-8.05 (m, 3H), 7.78 (s, 1H), 7.71-7.68 (t, J=7.8 Hz, 1H), 7.24-7.19 (m, 2H), 3.66 (s, 2H), 1.41 (s, 6H). MS (ESI) m/z: Calculated for C23H16F4N4O3: 474.13. found: 475.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-675366e807a5419fb08882fac4d29dd7 |
| Source note | uspto-grants-2014_12 |