2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine → HCID 67324570, compound

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Reaction Steps

This compound was synthesized from 2-(2-(4-fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine and 3-(5-(2,2,2-trifluoroacetyl)furan-2-yl)benzoic acid as described in example 8 step 6 (20 mg, yield 6%). 1H NMR (400 MHz, DMSO-d6) δ 8.52-8.49 (t, J=6.2 Hz, 1H), 8.30-8.29 (t, J=1.6 Hz, 1H), 8.09-8.06 (dt, J=8.1 Hz, 1.2 Hz, 1H), 8.01-7.98 (m, 4H), 7.94-7.92 (dt, J=8.1 Hz, 1.2 Hz, 1H), 7.66-7.62 (t, J=7.8 Hz, 1H), 7.51-7.50 (d, J=4.0 Hz, 1H), 7.35-7.31 (t, J=9.0 Hz, 2H), 3.52-3.50 (d, J=6.4 Hz, 2H), 1.29 (s, 6H). MS (ESI) m/z: Calculated for C26H20F4N2O4: 500.14. found: 499.4 (M−H)−.

Provenance & Evidence