5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid → HCID 67379542, compound

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Reaction Steps

This compound was synthesized from 2-(2-(4-chlorophenyl)oxazol-4-yl)ethanamine and 5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid as described in example 8 step 6 (14 mgs, 10% yield). 1H NMR (CDCl3) δ 9.45 (s, 1H), 9.29 (s, 1H), 8.84 (s, 1H), 7.97 (d, J=8.4 Hz, 1H), 7.80 (s, 1H), 7.57 (s, 1H), 7.43 (d, J=8.1 Hz, 1H), 7.26 (s, 1H), 3.85 (d, J=5.1 Hz, 2H), 2.93 (t, J=5.4 Hz, 2H). MS (ESI) m/z: Calculated for C20H13ClF3N5O3: 463.07. found: 464.1 (M+H)+.

Provenance & Evidence