HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid → HCID 71212765, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid | HCID 67324216 | — |
| Reactant | HCID 67325368 | HCID 67325368 | — |
| Product | HCID 71212765 | HCID 71212765 | 13% |
Reaction Steps
This compound was synthesized from 2-methyl-2-(2-phenyloxazol-4-yl)propan-1-amine and 5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid as described in example 8 step 6 (19 mgs, 13% yield). 1H NMR (CDCl3) δ 9.45 (t, J=9.0 Hz, 1H), 9.35 (s, 1H), 8.42 (s, 1H), 8.03 (s, 2H), 7.51-7.40 (m, 4H), 3.62 (bs, 2H), 1.42 (s, 6H). MS (ESI) m/z: Calculated for C22H18F3N5O3: 457.14. found: 458.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-580b192b63ad47639f8db13575cad077 |
| Source note | uspto-grants-2014_12 |