Methyl beta-alanate → HCID 67324027, compound

HRID 1397453Notes

Reaction equation

HRID 1397453 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]([O:6][CH3:7])=[O:5].[F:8][C:9]([F:25])([F:24])[C:10]1[O:14][N:13]=[C:12]([C:15]2[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=2)[C:18](O)=[O:19])[N:11]=1>>[F:24][C:9]([F:8])([F:25])[C:10]1[O:14][N:13]=[C:12]([C:15]2[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=2)[C:18]([NH:1][CH2:2][CH2:3][C:4]([O:6][CH3:7])=[O:5])=[O:19])[N:11]=1

Participants

3

Reactant 2

HCID 192794Methyl beta-alanateHCID 251808543-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid

Product 1

HCID 67324027HCID 67324027, compoundYield 75%

Procedure

This compound was synthesized from methyl 3-aminopropanoate and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (120 mgs, yield 75%). MS (ESI) m/z: Calculated for C14H12F3N3O4: 343.08. found: 344.1 (M+H)+.

Sources & evidence

ORD record
ord-5666dde438724c6a9b37b2ce9e0fb84d
Source dataset
uspto-grants-2014_12
Patent number
US08901156B2

Reaction notes

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