HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine → HCID 53345125, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine | HCID 67323086 | — |
| Reactant | HCID 67323660 | HCID 67323660 | — |
| Product | HCID 53345125 | HCID 53345125 | 14% |
Reaction Steps
This compound was synthesized from 2-(2-(4-fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine and 3-(5-(2,2,2-trifluoroacetyl)furan-3-yl)benzoic acid as described in example 8 step 6 (30 mg, yield 14%). 1H NMR (400 MHz, DMSO-d6) δ 8.91 (s, 1H), 8.40-8.35 (m, 2H), 8.16 (m, 1H), 8.02-7.94 (m, 4H), 7.82-7.80 (m, 1H), 7.57-7.53 (t, J=7.8 Hz, 1H), 7.36-7.31 (t, J=9.0 Hz, 2H), 3.53-3.51 (d, J=6.1 Hz, 2H), 1.30 (s, 6H). MS (ESI) m/z: Calculated for C26H20F4N2O4: 500.14. found: 499.5 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-7572e5bdc7024b6aac9b159f39b6bc59 |
| Source note | uspto-grants-2014_12 |