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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397468Generated: November 1, 2026

2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine → HCID 53345125, compound

https://huagongshe.com/reaction/1397468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amineHCID 67323086—
ReactantHCID 67323660HCID 67323660—
ProductHCID 53345125HCID 5334512514%

Reaction Steps

This compound was synthesized from 2-(2-(4-fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine and 3-(5-(2,2,2-trifluoroacetyl)furan-3-yl)benzoic acid as described in example 8 step 6 (30 mg, yield 14%). 1H NMR (400 MHz, DMSO-d6) δ 8.91 (s, 1H), 8.40-8.35 (m, 2H), 8.16 (m, 1H), 8.02-7.94 (m, 4H), 7.82-7.80 (m, 1H), 7.57-7.53 (t, J=7.8 Hz, 1H), 7.36-7.31 (t, J=9.0 Hz, 2H), 3.53-3.51 (d, J=6.1 Hz, 2H), 1.30 (s, 6H). MS (ESI) m/z: Calculated for C26H20F4N2O4: 500.14. found: 499.5 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901156B2
Source datasetuspto-grants-2014_12
ORD IDord-7572e5bdc7024b6aac9b159f39b6bc59
Source noteuspto-grants-2014_12