3-Carboxyphenylboronic acid → HCID 67324493, compound

Participants

Reaction Steps

This compound was synthesized from 1-(4-bromothiophen-2-yl)-2,2,2-trifluoroethanone and 3-carboxyphenylboronic acid as described in example 88 step 3 (400 mg, yield 46%) as a pale yellow solid. 1H NMR (400 MHz, DMSO-d6) δ 13.19 (br s, 1H), 8.85 (d, J=1.2 Hz, 1H), 8.50 (s, 1H), 8.29 (m, 1H), 8.10-8.08 (d, J=7.6 Hz, 1H), 7.96-7.94 (d, J=7.6 Hz, 1H), 7.62-7.59 (t, J=7.8 Hz, 1H). MS (ESI) m/z: Calculated for C13H7F3O3S: 300.01. found: 298.9 (M−H)−.

Provenance & Evidence