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HRID1398098

反应详情

EQUATION

反应方程式

HRID 1398098 的结构方程式

REACTANTS

反应物

2
结构：N
HCID222

Ammonia gas

H3N

结构：CN(C)C(=O)[C@H]1CC[C@H]2O[C@H]2C1
HCID58084195

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)C(=O)[C@H]1CC[C@@H](O)[C@H](N)C1
HCID66657052

Cyclohexanecarboxamide, 3-amino-4-hydroxy-N,N-dimethyl-, (1S,3R,4R)-

C9H18N2O2

CONDITIONS

反应条件

温度
40 °C

PROCEDURE

实验过程

A 28% aqueous ammonia solution (5 ml) was added to (1S,3S,6R)—N,N-dimethyl-7-oxabicyclo[4.1.0]heptane-3-carboxamide (10) (1 g) at room temperature. The mixed solution was stirred at 40° C. for hours, and then, the solvent was concentrated under reduced pressure to obtain (1S,3R,4R)-3-amino-4-hydroxy-N,N-dimethylcyclohexanecarboxamide (1.18 g).

WORKUP

后处理

  1. concentrationthe solvent was concentrated under reduced pressure