HCID 68181591, compound → HCID 60164282, compound

Participants

Reaction Steps

The title compound was prepared by the procedure described in Example 2 (Step 2-b) by reacting 4-(6-bromo-1H-indazol-1-yl)pyrimidin-2-amine with 2-(1H-pyrazol-4-yl)but-3-yn-2-ol. The reaction was carried out at 75° C. for 1 hr: 1H NMR (500 MHz, DMSO) delta 1.81 (3H, s), 5.95 (1 H, br. s.), 6.93-7.17 (3H, m), 7.38 (1H, d, J=9.30 Hz), 7.70 (2H, br. s.), 7.88 (1H, d, J=8.35 Hz), 8.31 (1H, d, J=5.52 Hz), 8.49 (1H, s), 8.91 (1H, s), 12.71 (1H, br. s.); LC-MS: m/z=+346.50 (M+H)+.

Provenance & Evidence