4-[6-Bromo-2-(trichloromethyl)-1,3-benzodiazol-1-yl]pyrimidin-2-amine → 4-[6-iodo-2-(trichloromethyl)-1H-1,3-benzodiazol-1-yl]pyrimidin-2-amine

関与物質

反応手順

The title compound was prepared by procedure described for 4-[6-bromo-2-(trichloromethyl)-1H-1,3-benzodiazol-1-yl]pyrimidin-2-amine, by replacing 4-N-(2-amino-5-bromophenyl)pyrimidine-2,4-diamine with 4-N-(2-amino-5-iodophenyl)pyrimidine-2,4-diamine: 1H NMR (500 MHz, DMSO) delta 1.91 (3H, s), 7.01 (1H, d, J=5.1 Hz), 7.22 (2H, s), 7.77-7.69 (3H, m), 8.58 (1H, d, J=5.0 Hz), 11.97 (1H, s); LC-MS: m/z=+454/456/458 (M+H)+.

情報源と証拠