HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → 3, 4, 5-tris(benzyloxy)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 5-Methoxytryptamine | HCID 1833 | — |
| Reactant | 3,4,5-Tris(benzyloxy)benzoic Acid | HCID 11133969 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3, 4, 5-tris(benzyloxy)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)benzamide | HCID 66803552 | — |
Reaction Steps
2g was synthesized by the condensation of 1b (480 mg, 1.09 mmol) and 5-methoxy tryptamine (248 mg, 1.308 mmol) using standard EDC coupling method and was isolated as white solid (565 mg, 84%) by elution with 0.5% methanol in chloroform. Rf: 0.517 (1.6% methanol in chloroform); mp: 125-128° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901317B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-a62e7664cfa34ab39b95f9aa5ba3ae5c |
| Source note | uspto-grants-2014_12 |