HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68736178, compound → 3-Amino-4-methyl-6-(pyrrolidin-1-yl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68736178 | HCID 68736178 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Amino-4-methyl-6-(pyrrolidin-1-yl)pyridine | HCID 66907963 | 99% |
Reaction Steps
A mixture of 4-methyl-5-nitro-2-pyrrolidin-1-ylpyridine (2.08 g, 10.0 mmol) and 10% palladium on carbon (208 mg) in tetrahydrofuran (10 mL) was stirred under hydrogen atmosphere at room temperature for 16 hr. Catalyst was removed by filtration and the filtrate was concentrated in vacuo to give the title compound (1.76 g, 9.89 mmol, 99%), as a purple solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901141B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-5a17b7db1b0e47148e32451c78d2e64c |
| Source note | uspto-grants-2014_12 |