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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1398771Generated: November 1, 2026

HCID 68736178, compound → 3-Amino-4-methyl-6-(pyrrolidin-1-yl)pyridine

https://huagongshe.com/reaction/1398771

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68736178HCID 68736178—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
Product3-Amino-4-methyl-6-(pyrrolidin-1-yl)pyridineHCID 6690796399%

Reaction Steps

A mixture of 4-methyl-5-nitro-2-pyrrolidin-1-ylpyridine (2.08 g, 10.0 mmol) and 10% palladium on carbon (208 mg) in tetrahydrofuran (10 mL) was stirred under hydrogen atmosphere at room temperature for 16 hr. Catalyst was removed by filtration and the filtrate was concentrated in vacuo to give the title compound (1.76 g, 9.89 mmol, 99%), as a purple solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901141B2
Source datasetuspto-grants-2014_12
ORD IDord-5a17b7db1b0e47148e32451c78d2e64c
Source noteuspto-grants-2014_12