1-(Difluoromethyl)-1H-pyrazole-3-carboxylic acid → N-[3-(2-amino-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-4-yl)-4-fluorophenyl]-1-(difluoromethyl)pyrazole-3-carboxamide
Reaction equation
[F:21][CH:22]([n:23]1[n:24][c:25]([C:28](=[O:29])[OH:30])[cH:26][cH:27]1)[F:31].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1)[C:28]([c:25]1[n:24][n:23]([CH:22]([F:21])[F:31])[cH:27][cH:26]1)=[O:29]Participants
3
Sources & evidence
- ORD record
- ord-64507c436c294200959327f63f7e4527
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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