HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-4-phenyl-1H-1,2,3-triazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phenylacetylene | HCID 10821 | — |
| Reactant | 1-(2-Azidoethoxy)-2-(2-methoxyethoxy)ethane | HCID 10375240 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-4-phenyl-1H-1,2,3-triazole | HCID 117722885 | — |
Reaction Steps
1-azido-2-(2-(2-methoxyethoxy)ethoxy)ethane (15.0 g, 79 mmol) was mixed with phenylacetylene (8.10 g, 79 mmol) in a 1:3 solution of water:butanol. The mixture was rotovap and the product extracted in ethanolamine and washed multiple times with water and brine, producing 1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-4-phenyl-1H-1,2,3-triazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906135B1 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-53cc1d9cb95848769f720fccd4530399 |
| Source note | uspto-grants-2014_12 |