Methyl iodide → HCID 178496246, compound

HRID 1399388Notes

Reaction equation

HRID 1399388 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[N:13]=[N:12]1.[I:22][CH3:23]>C(#N)C>[I-:22].[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[N+:13]([CH3:23])=[N:12]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 1177228851-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-4-phenyl-1H-1,2,3-triazole

Product 1

HCID 178496246HCID 178496246, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The 1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-4-phenyl-1H-1,2,3-triazole was refluxed with excess iodomethane in acetonitrile for more than 12 hours and concentrated after cooling to room temperature. The product was rinsed with organic solvent, recrystallized with ethyl acetate and dried in vacua. The following 1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-3-methyl-4-phenyl-1H-1,2,3-triazol-3-ium iodide structure was confirmed:

Workup

  1. concentrationconcentrated
  2. washThe product was rinsed with organic solvent
  3. customrecrystallized with ethyl acetate
  4. customdried in vacua

Sources & evidence

ORD record
ord-b4083ef839d64a2988d74521ce03064e
Source dataset
uspto-grants-2014_12
Patent number
US08906135B1

Reaction notes

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