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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1399411Generated: November 1, 2026

2-Bromo-5-ethylthiophene → 2-(3,5-Difluoro-4'-ethylbiphenyl-4-yl)-5-ethylthiophene

https://huagongshe.com/reaction/1399411

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-ethylthiopheneHCID 22729112—
Reactant4'-Ethyl-3,5-difluoro-4-biphenylboronic acidHCID 66626071—
Product2-(3,5-Difluoro-4'-ethylbiphenyl-4-yl)-5-ethylthiopheneHCID 58028445—

Reaction Steps

The compound 2-(3,5-difluoro-4′-ethylbiphenyl-4-yl)-5-ethylthiophene (PUS-2-2) is prepared analogously to Example 2 from 4′-ethyl-3,5-difluoro-4-biphenylboronic acid and 2-bromo-5-ethylthiophene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08906261B2
Source datasetuspto-grants-2014_12
ORD IDord-e3e5dbd78c414075aa6d7acf4783008a
Source noteuspto-grants-2014_12