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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1399414Generated: October 31, 2026

2-Bromo-5-ethylthiophene → 2-(4'-Ethyl-2,6-difluorobiphenyl-4-yl)-5-ethylthiophene

https://huagongshe.com/reaction/1399414

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-ethylthiopheneHCID 22729112—
Reactant4'-Ethyl-2,6-difluoro-4-biphenylboronic acidHCID 66625190—
Product2-(4'-Ethyl-2,6-difluorobiphenyl-4-yl)-5-ethylthiopheneHCID 58028454—

Reaction Steps

The compound 2-(4′-ethyl-2,6-difluorobiphenyl-4-yl)-5-ethylthiophene (SUP-2-2) is prepared analogously to Example 1 from 4′-ethyl-2,6-difluoro-4-biphenylboronic acid and 2-bromo-5-ethylthiophene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08906261B2
Source datasetuspto-grants-2014_12
ORD IDord-d721801986a84c6c98021cc7a854e9f3
Source noteuspto-grants-2014_12