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HRID1399436

反应详情

EQUATION

反应方程式

HRID 1399436 的结构方程式

REACTANTS

反应物

3
结构：C[C@H](N)C(=O)O
HCID5950

L-​Alanine

C3H7NO2

结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：O=C(O)c1c([N+](=O)[O-])cccc1[N+](=O)[O-]
HCID119206

Benzoic acid, 2,6-dinitro-

C7H4N2O6

PRODUCTS

生成物

1
结构：C[C@H](NC(=O)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)O
HCID86713104

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=C(Cl)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-]
溶剂HCID88401

2,4-Dinitrobenzoyl chloride

C7H3ClN2O5

PROCEDURE

实验过程

The reaction of 2,4-dinitrobenzoyl chloride (prepared from 2,4-dinitrobenzoic acid, 2 g and SOCl2, 20 mL) with L-alanine (1.04 g, 11.79 mmol) in the presence of Na2CO3 (1.24 g, 11.79 mmol) as described in intermediate 2 gave the title compound as an off-white color solid (2.08 g, 78%), mp 194-196° C. 1H NMR (400 MHz, DMSO-d6): δ 12.77 (1H, s), 9.25 (1H, d, J=7.6 Hz), 8.77 (1H, d, J=2.0 Hz), 8.63 (1H, dd, J=8.4, 2.0 Hz), 7.87 (1H, d, J=8.4 Hz), 4.44 (1H, pentet, J=7.3 Hz), 1.38 (3H, d, J=7.2 Hz); LC-MS (negative ion mode): m/z 282 (M−H)−.