1-methyl-1H-pyrazole-4-sulfonyl chloride → N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]phenyl}-1-methyl-1H-pyrazole-4-sulfonamide

HRID 139955Notes

Reaction equation

HRID 139955 reaction equation
[CH3:23][n:24]1[n:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[Cl:32])[cH:28]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:16]3[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:10][c:11]([CH:13]([CH3:14])[CH3:15])[s:12]2)[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:16]3[cH:17][c:18]([NH:19][S:29]([c:27]4[cH:26][n:25][n:24]([CH3:23])[cH:28]4)(=[O:30])=[O:31])[cH:20][cH:21][cH:22]3)[n:10][c:11]([CH:13]([CH3:14])[CH3:15])[s:12]2)[n:7]1

Participants

3

Reactant 2

HCID 170247301-methyl-1H-pyrazole-4-sulfonyl chlorideHCID 579900463-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]aniline

Product 1

HCID 57989849N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]phenyl}-1-methyl-1H-pyrazole-4-sulfonamide

Sources & evidence

ORD record
ord-6cf37fed290845bb9108de076d61f631
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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