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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1399641Generated: October 29, 2026

Sodium Hydroxide → 2-[4-Methyl-6-(1-methylindol-5-yl)-2-phenyl-pyrimidin-5-yl]pentanoic acid

https://huagongshe.com/reaction/1399641

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantMethyl 2-(4-methyl-6-(1-methyl-1H-indol-5-yl)-2-phenylpyrimidin-5-yl)pentanoateHCID 66955926—
SolventMethanolHCID 887—
Product2-[4-Methyl-6-(1-methylindol-5-yl)-2-phenyl-pyrimidin-5-yl]pentanoic acidHCID 6695553077.2%

Reaction Steps

This compound was prepared according to general procedure D from methyl 2-(4-methyl-6-(1-methyl-1H-indol-5-yl)-2-phenylpyrimidin-5-yl)pentanoate (0.106 g; 0.256 mmol), sodium hydroxide 10N (0.256 mL; 2.56 mmol) in methanol (2.5 mL) to afford 0.079 g (76%) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08906906B2
Source datasetuspto-grants-2014_12
ORD IDord-08358328ee7c47e795804e614b1d52ae
Source noteuspto-grants-2014_12