Sodium Hydroxide → 2-(4-(Benzo[b]thiophen-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid

Participants

Role	Name	HCID	Charge
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	Methyl 2-(4-(benzo[b]thiophen-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate	HCID 66955566	—
Solvent	Methanol	HCID 887	—
Product	2-(4-(Benzo[b]thiophen-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid	HCID 66955352	81.3%

Reaction Steps

2 This compound was prepared according to general method D from methyl 2-(4-(benzo[b]thiophen-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.047 g; 0.113 mmol), sodium hydroxide 10N (0.113 mL; 1.13 mmol) in methanol (1.1 mL) to afford 0.037 g (79%) of the title compound as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08906906B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-8a4c180785b948e898465666fb04680b
Source note	uspto-grants-2014_12