2-(8-Fluoro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → HCID 66955310, compound

HRID 1399771Notes

Reaction equation

HRID 1399771 reaction equation
Cl[C:2]1[C:7]([CH:8]([CH2:13][CH2:14][CH3:15])[C:9]([O:11][CH3:12])=[O:10])=[C:6]([CH3:16])[N:5]=[C:4]([N:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)[N:3]=1.[F:23][C:24]1[CH:25]=[C:26](B2OC(C)(C)C(C)(C)O2)[C:27]([CH3:34])=[C:28]2[C:33]=1[O:32][CH2:31][CH2:30][CH2:29]2>>[F:23][C:24]1[CH:25]=[C:26]([C:2]2[C:7]([CH:8]([CH2:13][CH2:14][CH3:15])[C:9]([O:11][CH3:12])=[O:10])=[C:6]([CH3:16])[N:5]=[C:4]([N:17]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]3)[N:3]=2)[C:27]([CH3:34])=[C:28]2[C:33]=1[O:32][CH2:31][CH2:30][CH2:29]2

Participants

3

Reactant 2

HCID 596067662-(8-Fluoro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 86665653Methyl 2-(4-chloro-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoate

Product 1

HCID 66955310HCID 66955310, compound

Procedure

This compound is prepared according to general method E starting from methyl 2-(4-chloro-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoate and 2-(8-fluoro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.

Workup

  1. customThis compound is prepared

Sources & evidence

ORD record
ord-e0660ae50a39475abb9869b232e585e0
Source dataset
uspto-grants-2014_12
Patent number
US08906906B2

Reaction notes

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