HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(4-chloro-6-methyl-2-phenylpyrimidin-5-yl)pentanoate → HCID 66955962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(4-chloro-6-methyl-2-phenylpyrimidin-5-yl)pentanoate | HCID 86665652 | — |
| Reactant | HCID 178461633 | HCID 178461633 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 66955962 | HCID 66955962 | — |
Reaction Steps
This compound is prepared from methyl 2-(4-chloro-6-methyl-2-phenylpyrimidin-5-yl)pentanoate and ethylmagnesium chloride in THF at −10° C. in the presence of CuI as described in the following reference: Chemistry-A European Journal, 15(29), 7167-7179, S7167/1-S7167/121; 2009.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906906B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-b38cfe49c2ad45c29f83f1b72071e929 |
| Source note | uspto-grants-2014_12 |