HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 86696910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | HCID 86696909 | HCID 86696909 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 86696910 | HCID 86696910 | 42% |
Reaction Steps
Compound iii (20 mg; 0.042 mmol) was dissolved in THF-H2O (10:1, 11 mL). Conc. sulfuric acid (20 μL) and p-toluenesulphonic acid (0.7 mg, 4 mmol) were added and the mixture stirred at RT. The mixture was concentrated in vacuo and purified over silica (0-100% 0.1% FA (aq)-MeCN) yielding Compound 8 (8.8 mg, 42%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906902B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-d75dc4592146492dbe2df547dc096648 |
| Source note | uspto-grants-2014_12 |