4-(Trifluoromethylthio)bromobenzene → 4,4,5,5-Tetramethyl-2-{4-[(trifluoromethyl)sulfanyl]phenyl}-1,3,2-dioxaborolane

HRID 1400007Notes

Reaction equation

HRID 1400007 reaction equation
FC1(F)O[C:5]2[CH:7]=[CH:8][C:9]([B:11]3[O:15][C:14]([CH3:17])([CH3:16])[C:13]([CH3:19])([CH3:18])[O:12]3)=[CH:10][C:4]=2O1.BrC1C=CC([S:28][C:29]([F:32])([F:31])[F:30])=CC=1>>[CH3:17][C:14]1([CH3:16])[C:13]([CH3:18])([CH3:19])[O:12][B:11]([C:9]2[CH:10]=[CH:4][C:5]([S:28][C:29]([F:32])([F:31])[F:30])=[CH:7][CH:8]=2)[O:15]1

Participants

3

Reactant 2

HCID 7364134-(Trifluoromethylthio)bromobenzeneHCID 113121312,2-difluoro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzo[1,3]dioxole

Product 1

HCID 451588394,4,5,5-Tetramethyl-2-{4-[(trifluoromethyl)sulfanyl]phenyl}-1,3,2-dioxaborolane

Procedure

The title compound was prepared using methods analogous to those described for Intermediate 2 substituting 1-bromo-4-trifluoromethylsulfanyl-benzene as a starting material.

Sources & evidence

ORD record
ord-30356cf3ac884b79a2a8c96124766dcb
Source dataset
uspto-grants-2014_12
Patent number
US08906914B2

Reaction notes

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