Ethylamine → HCID 52939303, compound

HRID 1400126Notes

Reaction equation

HRID 1400126 reaction equation
[NH2:1][C:2]1[N:11]=[C:10]([C:12]([N:14]2[CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH2:15]2)=[O:13])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:23]([CH2:32][CH2:33][CH:34]([F:36])[F:35])([CH2:27][CH2:28][CH:29]([F:31])[F:30])[C:24]([OH:26])=O)[CH:8]=2)[N:3]=1.[CH2:37]([NH2:39])[CH3:38]>>[NH2:1][C:2]1[N:11]=[C:10]([C:12]([N:14]2[CH2:15][C:16]3[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:22]2)=[O:13])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:23]([CH2:27][CH2:28][CH:29]([F:31])[F:30])([CH2:32][CH2:33][CH:34]([F:35])[F:36])[C:24]([NH:39][CH2:37][CH3:38])=[O:26])[CH:8]=2)[N:3]=1

Participants

3

Reactant 2

HCID 6341EthylamineHCID 52939545HCID 52939545, compound

Product 1

HCID 52939303HCID 52939303, compound

Procedure

(Preparation by reaction of 2-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-2-(3,3-difluoropropyl)-5,5-difluoropentanoic acid [“A66”] with ethylamine);

Sources & evidence

ORD record
ord-482f7b9e71ba4e06b724711c93a57b74
Source dataset
uspto-grants-2014_12
Patent number
US08906930B2

Reaction notes

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