HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1400141Generated: November 2, 2026
Ethyl 2-methyl-2-(4-nitrophenyl)propanoate → Ethyl 2-(4-aminophenyl)-2-methylpropanoate
https://huagongshe.com/reaction/1400141
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl 2-methyl-2-(4-nitrophenyl)propanoate | HCID 15544079 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl 2-(4-aminophenyl)-2-methylpropanoate | HCID 15544083 | — |
Reaction Steps
8.7 g of ethyl 2-methyl-2-(4-nitrophenyl)propanoate are dissolved in 90 ml of tetrahydrofuran, 2 g of 5% Pd/C (52.3% of water) are added, and the mixture is stirred at 23° C. under a hydrogen atmosphere for 1 h. After aeration, the solid material is filtered off, and the filtrate is evaporated to dryness in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08906930B2 |
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| Source dataset | uspto-grants-2014_12 |
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| ORD ID | ord-e665f4e58bd34f85a555065369c5af8b |
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| Source note | uspto-grants-2014_12 |
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