HCID 67154048, compound → HCID 67154024, compound

Participants

Reaction Conditions

Reaction Steps

5.5 g of ethyl 2-(4-nitrophenyl)hexanoate are dissolved in 55 ml of tetrahydrofuran, 1 g of 5% Pd/C (52.3% of water) is added, and the mixture is stirred at 23° C. under a hydrogen atmosphere for 1 h. After aeration, the solid material is filtered off, and the filtrate is evaporated to dryness in vacuo. Yield: 4.8 g (99%) of ethyl 2-(4-aminophenyl)hexanoate (oil); LC-MS retention time: 1.73 min (“nonpolar” gradient).

Provenance & Evidence